News From the Field
Pac-Man-like CRISPR enzymes have potential for disease diagnostics
May 4, 2017
University of California, Berkeley, researchers have found 10 new variants of the Cas13a enzyme, the Pac-Man of the CRISPR world, that hold promise for disease diagnostics. Seven of these are like the known Cas13a enzyme, which binds RNA and once activated, indiscriminately chews up all RNA. Three, however, bind and cut at different RNA nucleotides and could be used in combination with the known Cas13a enzyme to simultaneously detect 2 types of viral RNA for multiplexed diagnostics.
University of California, Berkeley
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